You only live once, but that's not an excuse to make stupid decisions. Make calculated risk but be good at it, reduce mistakes and quickly learn from them.
Throughout my 5 years here in Binance, I've seen coins that rise and fall tremendously. Whether investing or trading, always be pessimistic and don't let your brain be overloaded with regrets and hesitation. True failures only happen when you chickened out from a defeat. We may fail but we must never be defeated nor even thinking of surrendering.