According to Jin10, U.S. stocks opened mixed, with the Dow Jones Industrial Average down 0.1%, the S&P 500 up 0.07%, and the Nasdaq up 0.1%. Major technology stocks were mixed, with Intel (INTC.O) down 2.8%, TSMC (TSM.N) up 1.1%, and Nvidia (NVDA.O) up 0.6%. Vaxcyte jumped 53% after the company said its pneumococcal vaccine met the goals of a late-stage clinical trial.