Claude Fable 5.2 topped a new life sciences image benchmark, with its score nearly doubling after tools were added.

Crypto Briefing’s report attributed the results to tool integration: the same model performed very differently with and without tools. This means that when evaluating these models, how tools are used and their cost-effectiveness are variables in their own right; looking only at the base model’s score doesn’t give the full picture.

· The report’s focus is on cost-effectiveness and tool-calling strategies, not the model’s biological understanding itself.

When evaluating models like these, would you look at the score without tools first, or the score with tools?