🧬 Google DeepMind launches AlphaGenome 2 to show how DNA changes act inside specific cells
AlphaGenome 2 predicts how DNA variants affect gene activity in individual human cell types and states, not just broad tissue averages. Trained on more than 100 million single-cell profiles across 68 tissues, it found nearly twice as many causal variants as the original model on a major immune-cell dataset (30% vs 16%). It can also adapt to a new single-cell experiment from a few dozen cells without retraining. It is free for non-commercial research via the AlphaGenome API, with commercial use in private preview, and is not approved for clinical use.
⭐ Pinpointing which cells a disease mutation actually affects is a key step toward finding new drug targets.
#AI
AlphaGenome 2 predicts how DNA variants affect gene activity in individual human cell types and states, not just broad tissue averages. Trained on more than 100 million single-cell profiles across 68 tissues, it found nearly twice as many causal variants as the original model on a major immune-cell dataset (30% vs 16%). It can also adapt to a new single-cell experiment from a few dozen cells without retraining. It is free for non-commercial research via the AlphaGenome API, with commercial use in private preview, and is not approved for clinical use.
⭐ Pinpointing which cells a disease mutation actually affects is a key step toward finding new drug targets.
#AI
